LINE-1 enhancer

Jachowicz JW, Bing X, Pontabry J, Bošković A, Rando OJ, Torres-Padilla ME. LINE-1 activation after fertilization regulates global chromatin accessibility in the early mouse embryo. Nat Genet. 2017 Oct;49(10):1502-1510. doi: 10.1038/ng.3945. Epub 2017 Aug 28. PMID: 28846101.

Percharde M, Lin CJ, Yin Y, Guan J, Peixoto GA, Bulut-Karslioglu A, Biechele S, Huang B, Shen X, Ramalho-Santos M. A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity. Cell. 2018 Jul 12;174(2):391-405.e19. doi: 10.1016/j.cell.2018.05.043. Epub 2018 Jun 21. PMID: 29937225; PMCID: PMC6046266.

Meng, S. et al. Young LINE-1 transposon 5′ UTRs marked by elongation factor ELL3 function as enhancers to regulate naïve pluripotency in embryonic stem cells. Nat. Cell Biol. 25, 1319–1331 (2023)​.

Pal, D. et al. H4K16ac activates the transcription of transposable elements and contributes to their cis-regulatory function. Nat. Struct. Mol. Biol. 30, 935–947 (2023)​.

Li X et al. LINE-1 transcription activates long-range gene expression. Nature Genetics(2024)